Institute for Research & Development

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“Building back better”: Task shifting is the way forward for Sri Lanka to address maternal mental health in the economic crisis

  • Mental Health
  • Journal Article

Key to successful global health collaborations: research, ethics and community engagement and involvement

  • Bioethics, Community Engagement And Involvement
  • Journal Article

Anticipated and experienced stigma and discrimination in the workplace among individuals with major depressive disorder in 35 countries: qualitative framework analysis of a mixed-method cross-sectional study

  • Mental Health
  • Journal Article

The Colombo Twin and Singleton Study (COTASS): Piloting the Feasibility of Collecting Nutritional Data and Extension of the Sample to Include Children of Twins

  • Food, Twin Research
  • Journal Article

Frequency of Consumption of Food Groups and Cardio-Metabolic Risk Factors: A Genetically Informative Twin Study in Sri Lanka

  • Food, Twin Research
  • Journal Article

All you Need is Trust? Public Perspectives on Consenting to Participate in Genomic Research in the Sri Lankan District of Colombo

  • Twin Research
  • Journal Article

The aftermath of war; mental health, substance use and their correlates with social support and resilience among adolescents in a post-conflict region of Sri Lanka

  • Mental Health
  • Journal Article

Ethics and research in psychiatry: Consent, capacity, and bioethics

  • Bioethics
  • Book Chapter
This chapter provides an overview of the principles underlying ethical procedures in psychiatric research, with a specific focus on populations with mental disorders and research

The relationship between independent and dependent life events and depression symptoms in Sri Lanka: a twin and singleton study

  • Twin Research
  • Journal Article
Life events have been associated with a variety of mental health conditions including depression. There is a scarcity of research in South Asia exploring the

Ethics, a critical friend of research

  • Bioethics
  • Journal Article
Ethics is perceived by some at least, as an opponent of research, or as a barrier or even a hindrance. Ethicists and researchers seem to

Determination of testicular estrogen receptor alpha expression of male chickens (Gallus domesticus) with age

  • Genetics
  • Journal Article
Estrogen activity, a central component of reproductive growth, is regulated by the receptor proteins, estrogen receptor alpha (ERα), and ER beta (ERβ) in chickens as

The association between emotional eating and depressive symptoms: a population-based twin study in Sri Lanka

  • Twin Research
  • Journal Article
This study investigated the genetic and environmental contributions to emotional overeating (EOE) and depressive symptoms, and their covariation, in a Sri-Lankan population, using genetic model-fitting

Effect of exogenous estrogen treatment on gonadal morphology, morphometry and estrogen receptor alpha mRNA expression in gonads of male chickens (Gallus domesticus)

  • Genetics
  • Journal Article
The current study was designed to investigate the post-hatching ERα expression in left gonads of male chickens along with gonadal morphology when the exogenous estradiol

Agreement between subjective and objective measures of sleep duration in a low-middle income country setting

  • Twin Research
  • Journal Article
Describe sleep duration in adult Sri Lankans and determine the bias and agreement of self-report and actigraphic assessments.

Literature Review for Identifying the Research Gaps on Taxonomy, Molecular Systematics and Conservation Status of Endemic Skink Genus Lankascincus (Squamata: Scincidae)

  • Genetics
  • Abstract
Sri Lanka harbours a rich endemism for skinks. As a key link in the food-chain, skinks support to balance the ecosystem and help retaining eco-cycles,

Effect of exogenous estradiol on the gonadal morphology and morphometry of the male chickens (Gallus domesticus)

  • Genetics
  • Abstract

Initial validation of zygosity determination questionnaire for Sri Lankan twins using STR analysis of 15 unlinked loci and the gender-determining marker amelogenin

  • Genetics
  • Abstract
Zygosity determination is an essential component in behavioural genetics which uses twins for research. Although genetic markers are considered gold-standard, questionnaire based methods are preferred

Determination of testicular estrogen receptor α expression of male chickens (Gallus Domesticus) with age

  • Genetics
  • Abstract
Estrogen activity within living cells is regulated by its receptor, estrogen receptor α (ER α) and estrogen receptor β (ER β) in chickens as in

Agricultural, Economical and Ecological Importance of Phoenix pusilla (Ceylon Date Palm) and Its Future Research Perspectives

  • Genetics
  • Abstract
Phoenix pusilla, is an underutilised fruit crop, and an untouched genetic resource, facing a severe genetic loss due to the negligence of the public and

Protein Overexpression in Different E. coli Strains for Industrial Scale Drug Development in Sri Lanka

  • Genetics
  • Abstract
Research and industrial scale protein overexpression for pharmaceutical products uses Escherichia coli (E. coli) strains due to their well-characterised genome and easy manipulation. This review

Comparison of DNA isolation and dominant and co-dominant molecular markers to reveal the genetic sex of Gallus domesticus (Domestic chickens)

  • Genetics
  • Abstract

The Colombo Twin and Singleton Follow-up Study: a population based twin study of psychiatric disorders and metabolic syndrome in Sri Lanka

  • Twin Research
  • Journal Article
The disease burden related to mental disorders and metabolic syndrome is growing in low-and middle-income countries (LMIC). The Colombo Twin and Singleton Study (COTASS) is

Sri Lankan Twin Registry Biobank: A Resource for Human Genetic Research in Sri Lanka

  • Genetics
  • Abstract
Bio banking is an innovave concept of storing and sharing biological samples for current and future research. Even though it is well established in the

Polymerase Chain Reaction (PCR) Optimization of Sex Chromosome Linked CHD Gene for Genetic Sexing of Domestic Chickens (Gallus domesticus)

  • Genetics
  • Abstract
Abstract Chromodomain Helicase DNA (CHD) binding protein loci is one of the sex chromosome linked gene found in most avian species including domestic chickens. CHD

Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts

  • Twin Research
  • Journal Article
Whether monozygotic (MZ) and dizygotic (DZ) twins differ from each other in a variety of phenotypes is important for genetic twin modeling and for inferences

Genetic and other risk factors for suicidal ideation and the relationship with depression

  • Suicide
  • Journal Article
There is a genetic contribution to the risk of suicide, but sparse prior research on the genetics of suicidal ideation.

Quality assurance of biospecimens for biobanking purposes: Sri Lankan Twin Registry Biobank

  • Genetics
  • Abstract
Quality assurance is a vital component in biobanking to assure integrity and viability of samples. Although standards are established for biobanking in the western world,

Developing a center for genetic research and capacity building of early-career scientists in Sri Lanka

  • Genetics
  • Abstract
Genetics plays an important role in health research. Shortage of infrastructure limits the genetics research output from within the country. Moreover poor practical and analytical

A systematic review of the Dementia Research in Sri Lanka

  • Systematic Reviews
  • Journal Article
The aim of this systematic review is to describe dementia research in Sri Lanka. This information will inform on dementia prevalence, person with dementia and

Integrating mental health into primary care for post‑conflict populations: A pilot study

  • Migration Research
  • Journal Article
Mental health care in post-conflict settings is often not prioritized, despite its important public health role. There is a salient gap in integrating mental health