Initial validation of zygosity determination questionnaire for Sri Lankan twins using STR analysis of 15 unlinked loci and the gender-determining marker amelogenin

27 Aug 2018
Publication
Abstract
Genetics

Authors

Warnakula, L., Cooray, R., Hapuarachchi, N.S., Jayaweera, K., & Sumathipala, A.

Publisher

Shifting focus from diseases to patients: Today’s vision, tomorrow’s reality, 131st Anniversary International Medical Congress, Sri Lanka Medical Association, Colombo, Sri Lanka.

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ISBN

Abstract

Introduction & Objectives
Zygosity determination is an essential component in behavioural genetics which uses twins for research.
Although genetic markers are considered gold-standard, questionnaire based methods are preferred in resource poor settings due to cost effectiveness.
The present study examines the validity of an adapted Sinhala version of a zygosity determination questionnaire using a panel of 16 Short Tandem Repeats (STRs).

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